Does buspirone ameliorate the susceptibility to central sleep apnea?
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چکیده
منابع مشابه
Sleep apnea and heart failure: Part II: central sleep apnea.
In the first part of this 2-part review, we provided a synopsis of the cardiovascular effects of normal sleep and an overview of the diagnostic, pathophysiological, and therapeutic implications of obstructive sleep apnea (OSA) in the setting of heart failure (HF). In this second part, we turn our attention to central sleep apnea (CSA), commonly referred to as Cheyne-Stokes respiration. This bre...
متن کاملEffect of episodic hypoxia on the susceptibility to hypocapnic central apnea during NREM sleep.
We hypothesized that episodic hypoxia (EH) leads to alterations in chemoreflex characteristics that might promote the development of central apnea in sleeping humans. We used nasal noninvasive positive pressure mechanical ventilation to induce hypocapnic central apnea in 11 healthy participants during stable nonrapid eye movement sleep before and after an exposure to EH, which consisted of fift...
متن کاملWhat is central sleep apnea?
Central sleep apnea (CSA) describes a group of conditions in which cessations in air flow occur without respiratory effort. In contrast, obstructive sleep apnea patients have ongoing respiratory effort during respiratory events. However, considerable overlap exists in the pathogenesis and clinical presentation of obstructive sleep apnea and CSA. A good working knowledge of the mechanisms underl...
متن کاملCentral apnea during stage 3,4 sleep.
A 45-year-old female who complained of frequent awakenings and excessive daytime sleepiness (Epworth Sleepiness Scale 16/24) was referred for a sleep study. Her husband reported that she had frequent pauses in her breathing during sleep with intermittent snoring and gasping. The patient began having sleep problems about 2 years before the sleep study. At that time she also developed severe pain...
متن کاملPathogenesis of obstructive and central sleep apnea.
Considerable progress has been made over the last several decades in our understanding of the pathophysiology of both central and obstructive sleep apnea. Central sleep apnea, in its various forms, is generally the product of an unstable ventilatory control system (high loop gain) with increased controller gain (high hypercapnic responsiveness) generally being the cause. High plant gain can con...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2021
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.01077.2020